Tirzepatide is a GLP-1 and GIP agonist, mimicking the action of incretin hormones that play a role in your appetite and digestion. Incretins are hormones released by your small intestine and are sent out to your body after you have eaten a meal. The incretins trigger insulin production and block other sources of sugar. This is how your body stabilizes your blood sugar. Tirzepatide also slows gastric emptying , which is how quickly food leaves your stomach after eating. This causes you to feel full longer, which decreases your appetite and aids in losing weight. Lastly, Tirzepatide works at the hunger center of your brain to dampen your appetite. Tirzepatide promotes weight loss by empowering you to eat less calories on a daily basis.